Large corporations welcome innovation and individualism in the same way the dinosaurs welcomed large meteors.

If you’re going to create, create a lot. Creativity is not like playing the slot machines, where failure to win means you go home broke. With creativity, if you don’t win, you’re usually no worse off than if you hadn’t played.

If you work in the city long enough, it begins to deal with you on a personal level. Streets reveal their moods. Sometimes the signal light loves you. Sometimes they fight you. When you're hunting for a new building, you hope the city is on your side. You have to use a little bit of thinking--you might call it the process of elimination--and you need a little bit of instinct, but not too much of either. If you think too hard, you overshoot your target and end up at the Pier or the Tenderloin. If you relax and let the city help, the destination does all the work for you.

Everything you learn becomes a shortcut for understanding something else.

Scientists will eventually stop flailing around with solar power and focus their efforts on harnessing the only truly unlimited source of energy on the planet: stupidity. I predict that in the future, scientists will learn how to convert stupidity into clean fuel.

Reporters are faced with the daily choice of painstakingly researching stories or writing whatever people tell them. Both approaches pay the same.

The surest way to identify those who won't succeed at weight loss is that they tend to say things like "My goal is to lose ten pounds." Weight targets often work in the short run. But if you need willpower to keep the weight off, you're doomed in the long run. The only way to succeed in the long run is by using a system that bypasses your need for willpower.