I think it is only in hindsight that you can determine whether something is a mistake or not.

Aside from the equivalent of blowing up the lab or letting a pathogen escape, the only failure is spending too long or too much money to learn.

In the early stages of innovation, your goal is to learn as much as you can as quickly as you can.

Have a core concept, but wrap it in a full business model.

It would be fun too to put some of the great philosophers and political scientists of the past couple centuries into a time machine, have them look at the world today, and see what they think. Imagine Schumpeter, Malthus, Hobbes, Nietzsche, Marx, and more! That would be good fun.

When you are motivating people to do amazing things, you have to win over both their rational side and their emotive side.

Some people who were central to former success aren't the right people for your future success.