Aside from the equivalent of blowing up the lab or letting a pathogen escape, the only failure is spending too long or too much money to learn.

You can increase the odds of spotting the weak points in your approach if you really think about the end-to-end business model you plan to follow - how you plan to create, capture, and deliver value.

I feel for today's leaders. I really do. They got to where they are by doing a series of jobs exceptionally well. And that doesn't help them at all with the challenges they now face.

All disruptive innovators make it easier and more affordable for people to do what matters to them, and follow a strategy that doesn't at first glance make sense to the market leader.

Creating the new increasingly is more than 50 percent of a top leader's job.

Now, I worry a bit about the TEDification of the world where style trumps substance, so hopefully you have a good blend of both!

A spreadsheet for an innovative idea reports the mathematical relationship between made up numbers. You can't cash a spreadsheet.