Even if you know a character really well, there's no formula for what jokes will work and what won't.
Seth MacFarlaneI'm not a fatalist. I'm not a religious person. I'm sure there are close calls that we're not even aware of hundreds of times a year. You cross the street, and if you'd crossed the street two minutes later, you'd have been hit by a car, but you'd never know it. I'm sure that kind of stuff happens all the time.
Seth MacFarlaneThe trend today is vampires, zombies, angels, all the stuff that puts me right to sleep. It's too bad because it's so much less interesting than the diversity of stories you can tell with science.
Seth MacFarlaneI'm wide open to getting married, but actors are not easy people to date. You end up sharing that person with this other mistress that is their career. I very much like the traditional courtship method of making a date. That's what they do in normal places, but Hollywood's not normal.
Seth MacFarlane