The traditional metaphor for careers is a ladder, but I no longer think that metaphor holds. It just doesn’t make sense in a less hierarchical world... Build your skills, not your resume. Evaluate what you can do, not the title they’re going to give you. Do real work. Take a sales quota, a line role, an ops job. Don’t plan too much, and don’t expect a direct climb. If I had mapped out my career when I was sitting where you are, I would have missed my career.

Your life's course will not be determined by doing the things that you are certain you can do. Those are the easy things. It will be determined by whether you try the things that are hard.

Real change will come when powerful women are less of an exception. It is easy to dislike senior women because there are so few.

I don't pretend there aren't biological differences, but I don't believe the desire for leadership is hardwired biology, not the desire to win or excel. I believe that it's socialization, that we're socializing our daughters to nurture and our boys to lead.

I wish I could just go tell all the young women I work with, all these fabulous women, 'Believe in yourself and negotiate for yourself. Own your own success.' I wish I could tell that to my daughter. But it's not that simple.

It is the ultimate luxury to combine passion and contribution. It's also a very clear path to happiness.

The most important thing we're doing differently is that we talk openly about gender at Facebook.