Focus does not mean saying yes, it means saying no.

It places value on experience versus intellectual understanding. I saw a lot of people contemplating things but it didn't seem to lead to too many places. I got very interested in people who had discovered something more significant than an intellectual, abstract understanding.

These technologies can make life easier, can let us touch people we might not otherwise. You may have a child with a birth defect and be able to get in touch with other parents and support groups, get medical information, the latest experimental drugs. These things can profoundly influence life. I'm not downplaying that.

Sometimes life hits you in the head with a brick. Don't lose faith.

You are all over the map, figure out the top 5 things you want to focus on and get rid of the rest.

I was in the parking lot, with the key in the car, and I thought to myself: If this is my last night on earth, would I rather spend it at a business meeting or with this woman? I ran across the parking lot, asked her if she'd have dinner with me. She said yes, we walked into town, and we've been together ever since.

It's hard to tell with these Internet startups if they're really interested in building companies or if they're just interested in the money. I can tell you, though: If they don't really want to build a company, they won't luck into it. That's because it's so hard that if you don't have a passion, you'll give up.