Unless you walk out into the unknown, the odds of making a profound difference in your life are pretty low.
Good managers have a bias for action.
Nothing good or great can be done in the absence of enthusiasm.
You can't think your way out of a box; you've got to act.
A while back, I came across a line attributed to IBM founder Thomas Watson. If you want to achieve excellence, he said, you can get there today. As of this second, quit doing less-than-excellent work.
Accept change as a friend. And don't take yourself too seriously.