All connections matter, but the people you depend upon matter most.

It is especially important for managers to know about, neuroplasticity, the greatest discovery in neuroscience in the past 20 years. It refers to the fact that the brain is remarkably plastic. It can grow and change for the better throughout life. In fact, "plastic" denotes the brain's ability to grow and change throughout life.

You brain does its best when it is doing a task it can do well. That's basic brain science.

No work is "most important." Or, put differently, all work is important but work done poorly becomes most important.

Young people beginning a career need to realize that there are lots of "buses" in life. More often than not, selecting which one to be on determines success or failure, joy or despair.

All connections matter, but the people you depend upon matter most.

Modern loneliness is an extraverted loneliness, in which the person is surrounded by many people and partakes of much communication but feels unrecognized and more alone and, although connected technically, isolated and even estranged emotionally.