Every game we play activates our brain, and it's the same brain we have in real life as we have in the game.

It seems like what happens when we play games is that we go into a psychological state called eustress, or positive stress. It's basically the same as negative stress in the sense that we get our adrenaline up, you know, our breathing rate quickens, our pulse quickens.

We can boost our immune systems by strengthening our social networks and decreasing stress.

We've been playing games since humanity had civilization - there is something primal about our desire and our ability to play games. It's so deep-seated that it can bypass latter-day cultural norms and biases.

Clinically speaking, depression is a pessimistic sense of your own capabilities, and despondent lack of energy.

When you strip away the genre differences and the technological complexities, all games share four defining traits: a goal, rules, a feedback system, and voluntary participation.

You can't play the same game every day for years. New games are key.