I told all of our original investors that they would lose their money for sure.

One of the things it was obvious you could do with an online store is have a much more complete selection.

You don't choose your passions; your passions choose you.

Invention is by its very nature disruptive. If you want to be understood at all times, then don't do anything new.

The smartest people are constantly revising their understanding, reconsidering a problem they thought they’d already solved. They’re open to new points of view, new information, new ideas, contradictions, and challenges to their own way of thinking.

The framework I found which made the decision incredibly easy was what I called — which only a nerd would call — a “regret minimization framework.” So, I wanted to project myself forward to age 80 and say, “Okay, now I’m looking back on my life. I want to have minimized the number of regrets I have.”

The world is littered with corpses that predicted technology in a particular arena was done. If there's another gigantic step change out there, we don't yet know what it is.