You should know that what wakes me up at night, what gets me running fast in the morning, and, frankly, what prompts me to lose any semblance of my habitual reserve is the conviction that work doesn't have to be this grim. We can do better.

You can find energizing moments in each aspect of your life, but to do so you must learn how to catch them, hold on to them, to feel the pull of their weight and allow yourself to follow where they lead.

It's a special person - and personality - who can lead a start-up to soaring success and sustain that success for the long term. Apple co-founder Steve Jobs and Facebook's Mark Zuckerberg are star examples.

Getting after this terrible, avoidable waste of human potentiality is what gets me out of bed every morning.

Google and Facebook, each in their own way, have revolutionized the delivery of advertising based on search and social networking, creating a sort of anti-Spam: targeted, relevant ads that a consumer might actually welcome rather than spurn.

Every company wants to know how to find and keep highly talented women in the workplace.

When you feel as though you can't do something, the simple antidote is action: Begin doing it. Start the process, even if it's just a simple step, and don't stop at the beginning.