AirBnB happened because Brian Chesky couldn't pay his rent, but did have some space.

The single word that matters most I think to keep the company productive as it grows is alignment.

As the company grows and about this 25 or so employee size, your main job shifts from building a great product to building a great company.

You can create value with breakthrough innovation, incremental refinement, or complex coordination. Great companies often do two of these. The very best companies do all three.

... if you talk to say any of the first 40 or 50 employees, they all feel like they were a part of the founding of the company.

The natural state of a start-up is to die; most start-ups require multiple miracles in their early days to escape this fate.

Stay focused and don't try to do too many things at once. Care about execution quality.