A wise friend once told me, 'Don't wear what fashion designers tell you to wear. Wear what they wear.'

For my first show at 'SNL', I wrote a Bill Clinton sketch, and during our read-through, it wasn't getting any laughs. This weight of embarrassment came over me, and I felt like I was sweating from my spine out. But I realized, 'Okay, that happened, and I did not die.' You've got to experience failure to understand that you can survive it.

George Clooney married Amal Alamuddin this year. Amal is a human rights lawyer who worked on the Enron case, was an advisor to Kofi Annan regarding Syria, and was selected for a three-person commission investigating rules of war violation in the Gaza Strip. So tonight, her husband is getting a lifetime achievement award.

Even when I was at 'SNL,' I didn't do impersonations. I always wanted to be the kind of person who could do them - I always thought they were the coolest thing on the show - but I didn't have any experience.

When actors are too good-looking, I can’t memorize them. For example, I have never seen a picture of Sienna Miller where I didn’t say, “That girl’s pretty. Who is that?

When you have a set of characters, you have to fall in love with them and care about them as each individual character.

In my limited experience, shows are like children. You can teach them manners and dress them in little sailor suits, but in the end, they're going to be who they're going to be.