I was taken to an examining room where a big butch nurse practitioner came in and asked me if I was pregnant. “No way!” Was I sexually active? “Nope!” Had I ever been molested? “Well,” I said, trying to make a joke, “Oprah says the only answers to that question are ‘Yes’ and ‘I don’t remember.’ ” I laughed. We were having fun. The nurse looked at me, concerned/annoyed.

You have to try your hardest to be at the top of your game and improve every joke you can until the last possible second, and then you have to let it go.

I went through a phase where I was sick of acting, I didn't want to do it anymore, I was bored with it and then I tried directing a movie and I was like: "Shoot, get back over there!" It made me appreciate acting more.

Only in comedy, by the way, does an obedient white girl from the suburbs count as diversity.

Growing up as a girl is always traumatizing, especially when you have the deadly combination of greasy skin and getting your boobs at ten. But I think it's good to grow up that way. It builds character.

You mostly know that you want to be funny, know that you have the desire. It's not like people who grow up beautiful and can look in the mirror and be like, I'm beautiful! Funny is more of a journey. And a desperate attempt.

If you care about [the characters] as if they were real, that always helps.