You ever mix two different groups of friends? That can be stressful. You always feel like you have to prep 'em. You're like, "These people over here, uh, they don't think I drink. And don't be thrown by my British accent."

Manhattan's probably one of the bluest parts in the country, and Indiana's definitely one of the redder states. I have sympathy for both sides.

I think being a doctor is really hard, and it's really this thankless, never-ending job. It's not even that you get done with a project. There are always sick people.

We wrote about having five kids and bringing them to church. A journalist at The Washington Post wrote this article where the headline was "The New Catholic Evangelism Of Jim Gaffigan." And it was a bit terrifying.

I grew up 45 minutes outside of Chicago.

I wish, in some ways, I was the type of comedian who could do something blistering and topical, but I'm the guy who gets stuck in the revolving door and thinks I should write about that.

That's my private business. Besides, the perception is that people that believe in God are stupid.