I'm often asked, "What is your favorite moment during the 30 years you hosted [The Tonight Show]?" I really don't have just one. The times I enjoyed the most were the spontaneous, unplanned segments that just happened, like Ed Ames' infamous "Tomahawk Toss" that produced one of the longest laughs in television history. When these lucky moments happen, you just go with them and enjoy the experience and high of the moment.

I wouldn't have the slightest interest in running for public office. I'd rather make jokes about politicians than become one of them.

If you're happy in what you're doing, you'll like yourself, you'll have inner peace.

Pie throwing is kind of a lost art, and although it may be a rather rudimentary, burlesque humor, there's something inherently funny about taking a pie in the face, under the right conditions.

Despite the fact that computer speeds are measured in nanoseconds and picoseconds - one billionth and one trillionth of a second, respectively - the smallest interval of time known to man is that which occurs in Manhattan between the traffic signal turning green and the taxi driver behind you blowing his horn.

I don't run with anybody's herd. I don't like crowds. I don't like going to fancy places. I don't like the whole nightclub scene. Cocktail parties drive me mad. So I do my job and I stay away from the rest of it.

Americans, too many of them, take themselves too seriously. You're going to get rapped - by the viewers, by the sponsors and by the network brass - if you joke about doctors, lawyers, dentists, scientists, bus drivers, I don't care who. You can't make a joke about Catholics, Negroes, Jews, Italians, politicians, dogs or cats. In fact, politicians, dogs and cats are the most sacred institutions in America.