Nihilism in American comedy came along way before 'The Simpsons.' There was a fairly nihilistic point of view to 'Saturday Night Live,' for instance, back in the beginning, and a lot of really dark comedy had a really anti-sentimental take on life.

Here's to alcohol: the cause of, and answer to, all of life's problems.

You can't keep blaming yourself. Just blame yourself once, and move on." Homer Simpson

Welcome to Suckersville, man.

American culture has a lot of great moustaches in its history. Mark Twain had a great moustache, Charlie Chaplin, Ben Turpin ... but Zappa, he's got the best moustache in American history. Got the moustache, right, and he's got that little thing on his chin, I think it's called an imperial, that is, like, the coolest thing. That's like one of the great icons of the twentieth century.

I'm normally not a praying man, but if you're up there, please save me, Superman. Homer Simpson

I love the idea that we put in jokes the kids don't get. And that later, when they grow up and read a few books and go to college and watch the show again, they can get it on a completely different level.