You just have to keep in mind that the important relationship is the relationship with the audience. That's what I try to do. Everything else is secondary.

The amazing thing about Freak Out! was that there was nothing quite like it in rock 'n roll at the time. It was really simultaneously crude and ugly, and incredibly sophisticated. The Beatles were funny, but there was nothing with the kind of sneer that you could feel in the music of Frank Zappa.

I went to Bali, and I was in a small village, and somebody who was with me showed a woman a little figurine of Bart and asked: 'Do you know who this is?' And she said: 'Mickey Mouse.'

Ah, sweet pity. Where would my love life be without it?

I like my beer cold, my TV loud, and my homosexuals flaming.

Solitude never hurt anyone. Emily Dickinson lived alone, and she wrote some of the most beautiful poetry the world has ever known... then went crazy as a loon." Lisa Simpson

People go into cartooning because they're shy and they're angry. That's when you're sitting in the back of a classroom drawing the teacher.