And ever since then [I] have set up businesses basically out of frustration. I mean, I set up Virgin Atlantic with one second-hand 747 because I hated the experience of flying on other people's airlines. And I thought, you know, I could try to create the kind of airline that I'd like to fly on. And people liked it.

When you are starting a business or going down any challenging endeavor, you are bound to encounter challenges. You are going to hit many roadblocks and obstacles. These are obstacles that would make any sane person want to throw in the towel and quit. If you want your business to succeed, you can’t do that (duh).

Realize that the people who are working with you, this is their life. You know, 80% of their time is spent at work. Make sure that they're proud of what they're doing, that they're enjoying what they're doing.

The quickest way to become a millionaire in the airline business is to start out as a billionaire.

With space travel, [it's] no different. You know, in 1990 I read the name Virgin Galactic Airways. Loved the name. And set out to try to find an engineer or rocket scientist in the world who could build a safe, reusable rocket that could take people to and from space and we could start a whole new era of commercial space travel.

Consider getting smaller in order to get bigger.

I never went into business just to make money - but I found that if I have fun, the money will come. I often ask myself, is my work fun and does it make me happy? I believe that the answer to that is more important than fame or fortune. If it stops being fun, I ask why? If I can't fix it, I stop doing it.