What are the five products you want to focus on? Get rid of the rest, because they’re dragging you down. They’re turning you into Microsoft. They’re causing you to turn out products that are adequate but not great.
Walter IsaacsonLeonardo da Vinci did not take received wisdom - whether from ancient classical thinkers or medieval scholars or from the Bible - without questioning it. And this was the beginning of the scientific method. This is another lesson for our time: that when we have evidence that contradicts a certain belief, we should be willing to change it. I think this made Leonardo, in some ways, a person who better understood the beauty of God's creation than a person who just takes all received wisdom from the Bible on faith.
Walter IsaacsonIf you want to be a great American, you have got to understand Ben Franklin, Thomas Jefferson, George Washington, how the American Revolution happened. I think if you want to be a good citizen of the digital age, it helps to feel comfortable with both the people and the ways of thinking that created the digital revolution.
Walter IsaacsonA popular feel for scientific endeavors should, if possible, be restored given the needs of the twenty-first century. This does not mean that every literature major should take a watered-down physics course or that a corporate lawyer should stay abreast of quantum mechanics. Rather, it means that an appreciation for the methods of science is a useful asset for a responsible citizenry. What science teaches us, very significantly, is the correlation between factual evidence and general theories, something well illustrated in Einstein's life.
Walter IsaacsonThe Mona Lisa, to me, is the greatest emotional painting ever done. The way the smile flickers makes it a work of both art and science, because Leonardo understood optics, and the muscles of the lips, and how light strikes the eye - all of it goes into making the Mona Lisa's smile so mysterious and elusive.
Walter Isaacson