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If we denote excitation as an end-effect by the sign plus (+), and inhibition as end-effect by the sign minus (-), such a reflex as the scratch-reflex can be termed a reflex of double-sign, for it develops excitatory end-effect and then inhibitory end-effect even during the duration of the exciting stimulus.
Charles Scott SherringtonThe end of knowledge is wisdom The end of culture is perfection The end of wisdom is freedom The end of education is character. And character consists of eagerness to renounce one's selfish greed.
Sai BabaFor you [God] are infinite and never change. In you "today" never comes to an end: and yet our "today" does come to an end in you, because time, as well as everything else, exists in you. If it did not, it would have no means of passing. And since your years never come to an end, for you they are simply "today."
Saint AugustineIn proportion as the exploitation of one individual by another is put an end to, the exploitation of one nation by another will also be put an end to. In proportion as the antagonism between classes within the nation vanishes, the hostility of one nation to another will come to an end.
Karl MarxThere is a lesson that I learned at twelve - the world does not end at the edge of a quad. There are people outside. The world does not end on the Fourth Level. There are people elsewhere. It took me two years to learn to apply the lesson - that neither does the world end with the Ship. If you want to accept life, you have to accept the whole bloody universe. The universe is filled with people, and there is not a single solitary spear carrier among them.
Alexei PanshinChristmas turns things tail-end foremost. The day and the spirit of Christmas rearrange the world parade. As the world arranges it, usually there come first in importance -- leading the parade with a big blare of a band -- the Big Shots. Frequently they are also the Stuffed Shirts. That's the first of the parade. Then at the tail end, as of little importance, trudge the weary, the poor, the lame, the halt, and the blind. But in the Christmas spirit, the procession is turned around. Those at the tail end are put first in the arrangement of the Child of Christmas.
Bill VaughanThe book I'm looking for,' says the blurred figure, who holds out a volume similar to yours, 'is the one that gives the sense of the world after the end of the world, the sense that the world is the end of everything that there is in the world, that the only thing there is in the world is the end of the world.
Italo CalvinoIn the end we just realize there's no end. It just goes on forever, in countlessly new forms. That's what's wonderful about the universe there's no escape from living. Death doesn't even end it.
Frederick LenzRight at this moment, I only want silence. I believe that the end of life is silence in the love people have for you. I've actually been running through what people have said about the end. Religion says that the end is one thing, because it serves their purpose. But great thinkers alike haven't always agreed. Shakespeare knew how to say it better than anyone else. Hamlet says 'The rest is silence.' And when you think of the noises of everyday life, you realize how particularly desirable that is. Silence.
Vincent PriceThe only way Congress can get one dollar to spend is to take that one dollar from Americans, borrow that one dollar from Americans, or inflate that one dollar from Americans. So, it's very much like the visual image of a swimming pool. A person notes there is a shallow end, so he takes the water out of the deep end and pours it in the shallow end, hoping to raise the height of the water in the pool - and you would call that person stupid.
Walter E. WilliamsI used to think the worst thing in life was to end up all alone. It's not. The worst thing in life is to end up with people who make you feel all alone.
Robin WilliamsIt felt like I'd been playing second-string football for a long time, when, suddenly, I was playing in the Super Bowl. Even when 'Basic Instinct' was a hit, I still felt like I was running with that ball toward the end zone. It took awhile for me to realize that I was already in the end zone with the ball down and the crowd screaming on its feet.
Sharon StoneI'd played a lot of best friends, and/or bad guys, which seems to be my lot in life. In romantic comedies there's always a best friend and the woman has a best friend and they always antagonise each other and then they end up together at the end of the movie.
Rob CorddryTo the former child migrants, who came to Australia from a home far away, led to believe this land would be a new beginning, when only to find it was not a beginning, but an end, an end of innocence - we apologise and we are sorry. To the mothers who lost the maternal right to love and care for their child - we apologise, and we are sorry.
Malcolm TurnbullO Rakshas, everything is always all right in the end. If it isn't all right, then it isn't the end
Ashwin SanghiEast Asia has prospered since the end of the Vietnam War, and Northeast Asia has prospered since the end of the Korean War in a way that seems unimaginable when you think of the history of the first half of the century.
William C. KirbyMy happiness is not the means to any end. It is the end. It is its own goal. It is its own purpose.
Ayn RandI don't seem to have any real strategy or pattern when it comes to love... At times I've been really guarded and careful and afraid to trust someone. But other times, you want to jump in headfirst. I've had moments of thinking, this is who I love and I don't care what anyone says. Those moments are beautiful and wild and exciting, but I've learned that those moments can end up hurting you in the end. I've been careful in love. I've been careless in love. And I've had adventures I wouldn't trade for anything.
Taylor SwiftI have a closet full of blazers and more striped shirts than any human could possibly wear. Somehow I think that I don't have striped shirts, and then I look at my closet and go, 'Oh, I have ten.' But then you always end up with your favourite striped shirt of the moment, and you don't end up wearing any of the other ones.
Jennifer MorrisonIn the name of religion, one tortures, persecutes, builds pyres. In the guise of ideologies, one massacres, tortures and kills. In the name of justice one punishes...in the name of love of one's country or of one's race hates other countries, despises them, massacres them. In the name of equality and brotherhood there is suppression and torture. There is nothing in common between the means and the end, the means go far beyond the end...ideologies and religion... are the alibis of the means.
Eugene IonescoThe means ought to be proportioned to the end; the persons from whose agency the attainment of any end is expected ought to possess the means by which it is to be attained.
Alexander HamiltonI was put into office by the people who believed in my idea that corruption is the root of poverty; that an end to corruption would mean an end to poverty.
Benigno Aquino IIIIt will come all right in the end. There is the steady impulse of your determination that sets you on your feet again after every downfall and breakdown. Gradually the obstacles are all overcome and your current becomes stronger. Everything comes right in the end. Steady determination is what is required.
Ramana MaharshiYou don't get a lot of life milestones in show business. It's really difficult to make things, and a lot of times you don't know you're at the end of something. With Mr. Show, I was only a writer and we knew we were going into the movie, and we thought, "Okay, like Monty Python, we're going to make five movies." And we didn't know it was the end. So it ended up being a bummer and such a terrible ending for Mr. Show. We never got to feel like, "Wow, we did it! We did something."
Scott AukermanWe know that Europe loves President Obama. He had adoring crowds. The press loves Obama. The question is how will this date end? Okay? The question is, to what end? Why do they love President Obama? They love his personal story, they love his wife. North Korea, China and Russia don't really care about Michelle's arms and, you know, whether they gave an iPod to the Queen, okay?
Laura IngrahamYou can just keep going and going and going, and you never get to the end of it because there is no end. The ending is a beginning. If you feel like that, then you accept that wherever you have to stop on this journey, you continue in some other form somewhere else.
Alice WalkerThe problem comes up because we ask the question in the wrong way. We supposed that solids were one thing and space quite another, or just nothing whatever. Then it appeared that space was no mere nothing, because solids couldn't do without it. But the mistake in the beginning was to think of solids and space as two different things, instead of as two aspects of the same thing. The point is that they are different but inseparable, like the front end and the rear end of a cat. Cut them apart, and the cat dies.
Alan WattsThe average man never really thinks from end to end of his life. The mental activity of such people is only a mouthing of cliches. What they mistake for thought is simply a repetition of what they have heard. My guess is that well over 80 percent of the human race goes through life without having a single original thought.
H. L. MenckenIt was as if this night were only one of thousands of nights, world without end, night curving into night to make a great arching line of which I couldnโt see the end, a night in which I roamed alone under cold, mindless stars.
Anne RiceThe modern way with God is to set him at a distance, if not to deny him altogether; and the irony is that modern Christians, preoccupied with maintaining religious practices in an irreligous world, have themselves allowed God to become remote...for churchmen who look at God through the wrong end of the telescope, so reducing him to pigmy proportions, cannot hope to end up as more than pigmy Christians.
J. I. PackerOnce you know the end of the story, every part of the story contains that end, and is only a way of reaching it.
Leah StewartThere never could be a man so brave that he would not sometime, or in the end, turn part or all coward; or so wise that he was not, from beginning to end, part ass if you knew where to look; or so good that nothing at all about him was despicable.
James Gould CozzensWhen you're a teenager, everything seems like the end of the world, and I don't think that's necessarily a silly thing. You're waking up and becoming aware that the world has problems and those problems affect you, whereas when you're young they don't seem to affect you that much even if you're aware of them. This dystopian trend picks up on that little part of your life where everything feels really extreme and it honors that part of your life and says, "Yeah. It is the end of the world. Look at it."
Veronica RothGrieve not; though the journey of life be bitter, and the end unseen, there is no road which does not lead to an end.
HafezIn the end, the truth always wins out. It always does, no matter how many times you tell a story that isn't true. In the end, the truth comes out. There's either video evidence or photographic evidence. I think the American people are smart consumers.
Gayle KingOnce you start to ask patients about their priorities, you discover what they're living for. Once you uncover that, it helps you, as a doctor, decide what to fight for. And when we do that, we often end up identifying limits to the kind of care that people want. One's assumption is that these people are going to live shorter lives, but what we're doing is protecting quality of life. In doing so, you sometimes end up helping people live longer. Certainly, you help people live better days and with more purpose in their lives.
Atul GawandeLet me end with an explanation of why I believe the move into space to be a human imperative. It seems to me obvious in too many ways to need listing that we cannot much longer depend upon our planet's relatively fragile ecosystem to handle the realities of the human tomorrow. Unless we turn human growth and energy toward the challenges and promises of space, our only other choice may be the awful risk, currently demonstrable, of stumbling into a cycle of fratricide and regression which could end all chances of our evolving further or of even surviving.
Gene RoddenberryThe idealism of the left is a very selfish idealism. In their war against 'the rich' and big business, they don't care how much collateral damage there is to workers who end up end up unemployed.
Thomas SowellI feel that I'm in a very interesting position, where I'm standing back to look at this change, at this moment in history of human beings. If the end of the civilization comes before the end of my life, that's lucky! I want to witness how this big story of humans ends.
Hiroshi SugimotoUnless devotion is given to the thing which must prove false in the end, the thing that is true in the end cannot enter.
Charles WilliamsAdults end up shading things and shading the truth, and you end up lying and telling people what they want to hear.
Chelsea HandlerI'm talking about when you're nearer the end of your life than the beginning. Now what do you think you think about then? The future? In the future I'm going to do this? Become that? What future? No. What you think is, 'How will I be regarded in the end?'
Christopher PlummerThere have been times where, let's say on LGBT issues, when we were trying to end Don't Ask, Don't Tell, and I got the Pentagon and Bob Gates, a Republican holdover from the [George W.] Bush administration, to authorize a study of how you might end Don't Ask, Don't Tell, headed up by Jeh Johnson, who at that time was a council to the Justice Department. And it was going to take a year to conduct that study, issue a report, and figure out how it might be implemented, what effect it would have on unit cohesion and military effectiveness.
Barack Obama